SIF - Societą Italiana di Farmacologia                                               "SIF - La Ricerca Farmacologica in Italia"

CHEMOTHERAPY

 

RESEARCH GROUP MEMBERS :

  1. Bertazzoni Minelli Elisa, P.O.
  2. Benini Anna, B.
  3. Mazzon Ilaria, B.

AFFILIATION :

Istituto di Farmacologia,

Facoltą di Medicina e Chirurgia

Universitą di Verona

ADDRESS: c/o Policlinico Borgo Roma

CITY: Verona

POSTAL CODE: 37134

TELEPHONE: 045-8098603, 8074244

FAX: 045-581111

PUBLICATIONS:

  1. BERTAZZONI MINELLI E., BENINI A., BEGHINI A.M., CERUTTI R., NARDO G., Bacterial faecal flora in healthy women of different ages. Microb. Ecol. Health Dis. 6: 43-51, 1993.
  2. BERTAZZONI MINELLI E., BENINI A. Effects of six antimicrobial drugs on rat intestinal flora: is the rat model of predictive value in clinical practice? Microb. Ecol. Health Dis. 6 : 53-66, 1993.
  3. BASSI C., PEDERZOLI P., VESENTINI S., CAVALLINI G., BOVO P., LOMBARDI D., ABBAS H., BENINI A., BERTAZZONI M.E. Behavior of antibiotics during human necrotizing pancreatitis. Antimicrob. Agents Chemother. 38: 830-836, 1994.
  4. CRUCIANI M., BERTAZZONI MINELLI E., MIRANDOLA M., LUZZATI R., MERIGHI M., LAZZARINI L., GATTI G., VENTO S., MAZZI R., LAZZARINI L., MALENA M., BENINI A., CAZZADORI A., PIEMONTE G., BASSETTI D., CONCIA E. Twice-weekly dapsone for primary prophylaxis of Pneumocystis carinii pneumonia in HIV-1 infection: comparative efficacy and pharmacokinetic data. Clin. Microbiol. Infection 2: 30-35, 1996.
  5. BERTAZZONI MINELLI E., BENINI A., BASSI C., ABBAS H., FALCONI M., PEDERZOLI P. Antimicrobial activity of human pancreatic juice and its interaction with antibiotics. Antimicrob. Agents Chemother. 40: 2099-2105, 1996.
  6. BERTAZZONI MINELLI E., BENINI A., MUNER A., BASSI C., ABBAS H., PEDERZOLI P. Pefloxacin penetration into human necrotic pancreatic tissue. J. Antimicrob. Chemother. 38: 237-243, 1996

RESEARCH GROUP MEMBERS:

  1. Braga Pier Carlo, P.A.
  2. Dal Sasso Monica, D.DR.
  3. Sala Maria Teresa, B.

AFFILIATION:

Centro di Studio e Ricerca in Farmacologia Respiratoria

Facoltą di Medicina e Chirurgia

Universitą degli Studi di Milano

ADDRESS: Via Vanvitelli, 32

CITY: Milano

POSTAL CODE: 20129

TELEPHONE: 02 - 70146-363, 233

FAX: 02 - 70146-363

PUBLICATIONS:

  1. BRAGA P.C., DAL SASSO M., MACI S, BONDIOLOTTI G., FONTI E., REGGIO S. Penetration of brodimoprim into human neutrophils and intracellular activity. Antimicr. Agents Chemother. 40: 2392-2398, 1996.
  2. BRENCIAGLIA M.I., FORNARA A.M., SCALTRITO M.M., BRAGA P.C., DUBINI F. Activity of amoxicillin, metronidazole, bismuth salicilate and six aminoglicosides against Helicobacter pylori. J. Chemother. 8 : 52-54, 1996.
  3. BRAGA P.C., MACI S., DAL SASSO M., BOHN M. Experimental evidences for the role of subinhibitory concentrations or rilopirox, nystatin and fluconazole on adherence of Candida spp. to vaginal epithelial cells. Chemoterapy, 42: 259-265, 1996.
  4. BRAGA P.C., REGGIO S. Correlation between reduction of surface hydrophobicity of S. aureus and the decrease in its adhesiveness induced by sub-inhibitory concentrations of brodimoprim. Pharmacol Res. 32 : 315-319, 1995.
  5. BRAGA P.C., MACI S., DAL SASSO M., PIATTI G., BOHN M. Alterations of surface morphology of Candida albicans produced by rilopirox: a scanning electron microscopy study. J. Chemother. 7 : 519-524, 1995.
  6. BRAGA P.C., DAL SASSO M., MACI S., ALLEGRA L., FONTI E., GHESSI A., REGGIO S. Influence of brodimoprim on polymorphonuclear leukocyte phagocytosis and oxidant radical production. Chemotherapy .41: 360-367, 1995.
  7. BRAGA P.C., PIATTI G., LIMOLI A., DAL SASSO M., MACI S. Neltenexine morphological investigation of protection against elastase-induced emphysema in rats. Drugs Expt. Clin. Res. 21: 51-57, 1995.
  8. BRAGA P.C., DAL SASSO M., MACI S., PIATTI G., DANNHORN D.R., BOHM M. Inhibition of Candida albicans adhesiveness to human buccal and vaginal cells by sub-MIC of rilopirox. Arzneim. Forsch Drug Res. 45: 84-87, 1995.
  9. BRAGA P.C., DAL SASSO M., MACI S., REGGIO S., PIATTI G. Influence of sub-inhibitory concentrations of brodimoprim and trimethoprim on the adhesiveness, hydrophobicity, hemagglutination and motility of Escherichia coli. Chemotherapy 41: 50-58, 1995.

RESEARCH GROUP MEMBERS:

  1. De Sarro Angela, P.A.
  2. Naccari Francesco, P.A.
  3. Ammendola Domenico, T.L.
  4. Nava Felice, B.

AFFILIATION:

Istituto di Farmacologia

Facoltą di Medicina e Chirurgia

Universitą di Messina

ADDRESS: Piazza XX Settembre, 4

CITY: Messina

POSTAL CODE: 98122

TELEPHONE: 090-712533

FAX: 090-661029

PUBLICATIONS:

  1. DE SARRO G.B. AND A. DE SARRO - Anticonvulsant properties of non-competitive antagonists of the N-methyl-D-Aspartate receptor in genetically epilepsy-prone rats: comparison with CPPene. Neuropharmacology, 32 : 51-58, 1993.
  2. DE SARRO G.B., DONATO DI PAOLA E., DE SARRO A., VIDAL M.J. - L-arginine potentiates excitatory amino acid-induced seizures elicited in the deep prepiriform cortex. Eur. J. Pharmacol., 230 : 151-158, 1993.
  3. DE SARRO A., ZAPPALą M., CHIMIRRI A., GRASSO S., DE SARRO G.B. - Quinolones potentiate cephazolin-induced seizures in DBA\2 mice. Ant. Agents Chemother., 37 : 1497-1503, 1993.
  4. DE SARRO G., ONGINI E., BERTORELLI R., AGUGLIA U., DE SARRO A. - Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA\2 mice. Eur. J. Pharmacol., 262 : 11-19, 1994.
  5. DE SARRO G., AMMENDOLA D., NAVA F., DE SARRO A. - Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA\2 mice. Brain Res., 671 : 131-140, 1995.
  6. DE SARRO A., AMMENDOLA D., ZAPPALą M., GRASSO S., DE SARRO G.B. - Relationship between structure and convulsant properties of some -lactam antibiotics following intracerebroventricular microinjection in rats. Ant. Agents Chemother., 39 : 232-237, 1995.
  7. SAIJA A., PRINCI P., LANZA M., SCALESE M., ARAMNEJAD E., DE SARRO A. - Systemic cytokine administration can affect blood-brain barrier permeability in the rat. Life Sci., 56 : 775-784, 1995.
  8. DE SARRO G., CHIMIRRI A., DE SARRO A., GITTO R., GRASSO S., GIUSTI P., CHAPMAN A. - GYKI 52466 and related 2,3-benzodiazepines as anticonvulsant agents in DBA/2 mice. Eur. J. Pharmacol., 294 : 411-422, 1995.
  9. DE SARRO G., NAVA F., AGUGLIA U., DE SARRO A. - Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice. Neuropharmacology, 35 : 153-158, 1996.
  10. DE SARRO G., DE SARRO A., AMMENDOLA D., PATEL S. - Lack of development of tolerance to anticonvulsant activity of CGP 37849 and CGP 39551 in genetically epilepsy-prone rats. Brain Res., 262 : 11-19, 1996.

RESEARCH GROUP MEMBERS :

  1. Fraschini Franco, P.O
  2. Ferrara Franca, A.O
  3. Scaglione Francesco, T.L
  4. Demartini Germana, T.L
  5. Dugnani Silvana, T.L
  6. Lucini Valeria, T.L
  7. Maccarinelli Giuseppina, T.L
  8. Nonno Romolo, D.DR
  9. Arcidiacono Mauro, D.DR
  10. Angeloni Deborah, D.DR
  11. Stankof Bojidar, Professore a Contratto
  12. Pannacci Marilou, B.

AFFILIATION :

Dipartimento di Farmacologia, Chemioterapia e Tossicologia Medica

Facoltą di Medicina e Chirurgia

Universitą degli Studi di Milano

ADDRESS: Via Vanvitelli, 32

CITY: Milano

POSTAL CODE: 20129

TELEPHONE: 02-718937, 70146.305

FAX: 02-718687

E-MAIL: Chemio@Imiucca.csi.unimi.it 

PUBLICATIONS:

  1. STANKOV, S. CAPSONI, V. LUCINI, J. FAUTECK, S. GATTI, B. GRIDELLI, G. BIELLA, B. COZZI AND F. FRASCHINI. Autoradiographic localization of putative melatonin receptors in the brains of two old world primates: Cercopithecus aethiops and Papio ursinus. Neuroscience 52:459-468, 1993
  2. SCAGLIONE, J.P. PINTUCCI, G.F. TASSI, G. MACCARINELLI, S. DUGNANI, G. DEMARTINI AND F. FRASCHINI. Penetration of clarithromycin into oral and respiratory tissues. Drug. Invest. 6:104-109, 1993
  3. STANKOV, M. GERVASONI, F. SCAGLIONE, R. PEREGO, D. COVA, L. MARABINI AND F. FRASCHINI. Primary pharmaco-toxicological evaluation of 2-iodio-melatonin, a potent melatonin agonist. Life Sci. 53:1357-1365, 1993
  4. SCAGLIONE, S. DUGNANI, G. DEMARTINI, M. SAUDELLI, G. GALMOZZI, F. FRASCHINI. The postantibiotic effect of clarithromycin and its major human metabolite, 14-hydroxy clarithromycin. J. Antimicrob. Chemother. 32:507-509, 1993
  5. STANKOV, MØLLER, V. LUCINI, S. CAPSONI, F. FRASCHINI. A carnivore species (Canis familiaris) expresses circadian melatonin rhythm in the peripheral blood and melatonin receptors in the brain. Eur J Endocrinol 131:191-200, 1994.
  6. ESPOSTI, M. MARIANI, G. DEMARTINI, V. LUCINI, F. FRASCINI, W. WITTKOWSKI, B. STANKOV. The adult human cerebellum is a target of the neuroendocrine system involved in the circadian timing. Neurosci Lett 179:60-64, 1994.
  7. SCAGLIONE, F. TRISCARI, G. DEMARTINI, M. ARCIDIACONO, C. COCUZZA, F. FRASCHINI. Concentrations of ceftibuten in bronchial secretions. Chemotherapy, 41:229-233, 1995.
  8. SCAGLIONE, S. DUGNANI, G. DEMARTINI, M. ARCIDIACONO, C. COCUZZA, F. FRASCHINI. Bactericidal kinetics of an in vitro infection model of once daily ceftriaxone plus amikacin against gram-positive and gram - bacteria. Chemotherapy, 41:239-246, 1995.
  9. FERINI-STRAMBI, A. OLDANI, M. ZUCCONI, B. STANKOV, C. CASTRONOVO, F. FRASCHINI, S. SMIRNE. Triazolam and melatonin effects on cardiac autonomic function during sleep. Clin. Neuropharmacol. 18:405-409,
  10. MAZZUCHELLI, S. CAPSONI, D. ANGELONI, F. FRASCHINI, B. STANKOV. The Melatonin receptor in the humain brain: cloning experiments and distribution studies. Mol. Brain Res., 39: 117-126, 1996.

RESEARCH GROUP MEMBERS:

  1. Giraldi Tullio, P.O.
  2. Perissin Laura, R.U.
  3. Zorzet Sonia, R.U. *
  4. Rapozzi Valentina, T.L.

AFFILIATION:

Sezione di Farmacologia, Dipartimento di Scienze e Tecnologie Biomediche

Facoltą di Medicina e Chirurgia

Universitą di Udine

* Sezione di Farmacologia, Dipartimento di Scienze Biomediche

Facoltą di Farmacia

Universitą di Trieste

ADDRESS: Piazzale Kolbe 4

CITY: Udine

POSTAL CODE: 33100

TELEPHONE: 0432-547117

FAX: 0432-547210

E-MAIL: giraldi@cc.uniud.it

PUBLICATIONS :

  1. CARTEI, G., CARTEI, F., CANTONE, A., CAUSARANO, D., GENCO, G., TOBALDIN, A.., INTERLANDI, G., AND GIRALDI, T. Cisplatin-cyclophosphamide-mitomycin combination chemothereapy with supportive care versus supportive care alone for treatment of metastasis non-small-cell lung cancer. JNCI 85: 794-800, 1993.
  2. PERISSIN, L., ZORZET, S., RAPOZZI, V., AND GIRALDI, T. A non-invasive simple method for measurement of urinary excretion of melatonin in undisturbed mice. J. Pineal Res. 15: 138-140, 1993.
  3. GIRALDI, T., PERISSIN, L:, ZORZET, S:, RAPOZZI, V:, AND RODANI, M.G. Metastasis and neuroendocrine system in stressed mice.. Intern. J. Neurosci. 74: 265-278, 1994.
  4. PERISSIN, L., ZORZET, S:; RAPOZZI, V., PAOLETTI, D:, AND GIRALDI, T. Seasonal dependency of the effects of experimental stressors on tumor metastasis in mice bearing Lewis lung carcinoma.. Chronobiologia 1/2 99-103, 1994.
  5. ZORZET, S., PERISSIN, L., RAPOZZI, V., PACOR, S., AND GIRALDI, T. Effects of prolonged treatment with dacarbazine on tumour metastatic potential in mice bearing Lewis lung carcinoma. Clin. Exp. Metastasis 13: 97-104, 1995.

RESEARCH GROUP MEMBERS :

  1. Mazzei Teresita, P.O.
  2. Mini Enrico, P.A.
  3. Novelli Andrea, R.U.
  4. Coronnello Marcella, T.L.
  5. Pesciullesi Alessandra, DDR
  6. Morganti Maria, D.DR.
  7. Carotti Stefania, B.
  8. Biondi Cristina, B.
  9. Fallani Stefania, B.
  10. Cassetta Maria Iris, B.
  11. Conti Silvia, B.
  12. Caciagli Barbara, B.
  13. Napoli Cristina, B.
  14. Nobili Stefania, S.S.
  15. Rossi Susanna, S.S.
  16. Dentico Patrizia, S.S.

AFFILIATION:

Dipartimento di Farmacologia Preclinica e Clinica "Mario Aiazzi Mancini"

Unitą di Chemioterapia

ADDRESS: Viale Morgagni 65,

CITY: Firenze

POSTAL CODE: 50134

TELEPHONE: 055-431720 (adm. of.), 4237-405, 411(operator), 4222603, 4237-410, 438, 439 (lab)

FAX: 055-416680; 4361613

E-MAIL : MAZZEI@Stat.Ds.UNIFI.IT

PUBLICATIONS :

  1. CAPACCIOLI, S., DI PASQUALE, G., MINI, E., MAZZEI, T.,AND CAPACCIOLI, S. Cationic lipids improve antisense oligonucleotide uptake and prevent degradation in cultured cells and in human serum. Biochem. Biophys. Res. Comm. 197: 818-825, 1993.
  2. DE LALLA, F., NOVELLI, A., PELLIZZER, G., MILOCCHI, F., VIOLA, R., RIGON, A., STECCA, C., DAL PIZZOL, V., FALLANI, S., AND PERITI, P. Regional and systemic prophylaxis with teicoplanin in monolateral and bilateral total knee replacement procedures: study of pharmacokinetics and tissue penetration. Antimicrobial Agents Chemother. 37: 2693-2698, 1993.
  3. MAZZEI, T., SURRENTI, C., NOVELLI, A., CRISPO, A., FALLANI, S., CARLą, V., SURRENTI, E. AND PERITI, P. Pharmacokinetics of azithromycin in patients with impaired hepatic function. J. Antimicrobial Chemother. 31: 57-63, 1993.
  4. QUATTRONE, A., PAPUCCI, L., MORGANTI, M., CORONNELLO, M., MINI, E., MAZZEI, T., COLONNA, F.P., GARBESI, A., AND CAPACCIOLI, S. Inhibition of MDR1 gene expression by antimessenger oligonucleotides lowers multiple drug resistance.Oncol. Res. 6: 311-320,1994.
  5. QUATTRONE, A., PAPUCCI, L., SCHIAVONE, N., MINI, E., AND CAPACCIOLI, S. Intracellular enhancement of intact antisense oligonucleotide steady-state levels by cationic lipids. Anticancer Drug Design. 9: 549-553, 1994.
  6. MAZZEI, T., TONELLI, F., NOVELLI, A., FICARI, F., MAZZONI, C., ANASTASI, A., AND PERITI, P. Comparative penetration of cefotetan into suction blister fluid and tissue homogenates in patients undergoing abdominal surgery. Cefotetan tissue penetration. Antimicrobial Agents Chemother. 38: 2221-2223, 1994.
  7. ARCANGELI, A., BIANCHI, L., BECCHETTI, A., FARAVELLI, L., CORONNELLO, M., MINI, E., OLIVOTTO, M., AND WANKE, E. A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells. J. Physiol. 455-471, 1995.
  8. CREE, I.A., PAZZAGLI, M., MINI, E., MAZZEI, T., HUNTER, E.M.M., SUTHERLAND, L.A., PINZANI, P., GERLI, A., AND ANDREOTTI, P.E. Methotrexate chemosensitivity by ATP bioluminescence in human leukemia cell lines and in breast cancer primary cultures: comparison of the TCA-100 assay with a clonogenic assay. Anticancer Drugs. 6: 398-404, 1995.
  9. MAZZEI, T., TONELLI, F., MINI, E., MAZZONI, P., PESCIULLESI, A., VALANZANO, R., FICARI, F., BIONDI, C.,AND PERITI, P. Flow cytometric analysis of DNA ploidy and cell proliferation in colorectal carcinoma. Anticancer Res. 15: 2247-2254, 1995.
  10. NOVELLI, A., MAZZEI, T., MELI, E., CONTI, S., FALLANI, S., PERITI, P. Clinical pharmacokinetics of meropenem after single or multiple im administration in patients. J. Antimicrobial Chemother. 37: 775-781, 1996.

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