SIF - Società Italiana di Farmacologia                                                                       "SIF - Congressi e Meetings"


 

Ettore Majorana Centre

International School of Pharmacology

 

59th Course: Nitric Oxide: basic research and clinical applications.

A NATO Advanced Study Institute

 

under the patronage of Italian Society of Pharmacology

 

Erice-Sicily: 7-17 September 2000

 

 

http://www.ccsem.infn.it/ccsem2000/Minuz2000.html

 

 


 

GENERAL INFORMATION

 

 

Persons wishing to attend the Course should apply in writing a letter to:

 

                                Dr. Pietro Minuz

                                Medicina Interna C

                                Policlinico GB Rossi

                                Piazzale LA Scuro

                                37134 Verona, Italy

                                Tel: ++39.045.8074414

                                Fax: ++39.045.508815

                                E-mail: minuz@borgoroma.univr.it

 

 

A copy of the letter should also be sent by fax.

 

Applicants should specify:

 

                                i) date and place of birth together with their present nationality;

                                ii) present position and academic qualifications;

 

 

No special application form is required

 

Young persons with only a few years experience should enclose a letter of recommendation from the head of their research group or from a senior scientist active in the field.

 

The total fee, which includes full board and lodging (arranged by the School), is $1000 USD. Thanks to the generosity of the sponsoring Institutions, limited support can be granted to some deserving students in need of financial help. Requests for this must be specified and justified in the letter of application.

 

 

Closing date for application: July 15th 2000

 

Participants are requested to arrive in Erice on September 7, 2000, no later than 5 p.m. More detailed information, including the timetable of the lectures, will be sent to successful applicants together with the acceptance letter.

 

 

Purpose of the course

 

In the past few years knowledge on the biology of nitric oxide has increased explosively. The impressive range of nitric oxide activities makes it of extreme importance to bring together different areas of research including: biochemistry and molecular biology of nitric oxide synthases and signalling, control systems of nitric oxide synthases, biochemistry of nitric oxide and peroxynitrite, methods for the detection of nitric oxide both in vitro and in vivo, mechanisms of the biological activities of nitric oxide in endothelial cell, smooth muscle cells and platelets, physiology of nitric oxide in cardiovascular, renal, nervous and respiratory systems, pathophysiology of nitric oxide metabolism in cardiovascular, respiratory and inflammatory diseases and finally the experimental and clinical pharmacology of nitric oxide synthase inhibitors, nitric oxide-donors and modulators of nitric oxide metabolism. The aim of the proposed Course is to give the opportunity to review all these different aspect of nitric oxide research.

 

The usual general approach of ASI Courses will be followed:

1- "state of the art" lecturers by invited lecturers and Course directors;

2- study groups; selected contributed papers; poster session and discussion.

 

 

Programme and lecturers

 

 

Robert F. FURCHGOTT

SUNY Health Science Center, NY, USA

 

Personal Perspective on Nitric Oxide: The Role of Accidental Discoveries.

 

 

Ferid MURAD

University of Texas Medical School, Huston, TX, USA 

 

Cellular Signalling with Nitric Oxide.

 

 

Dennis J. STUEHR

Lerner Research Institute Cleveland Clinic, Cleveland, USA

 

What Makes NOS a NOS? Enzyme Structure - Function Aspects

 

Controlling NOS Activity. Multiple Mechanisms Provide Clues for Biological Function

 

 

Joseph LOSCALZO

Whitaker Cardiovascular Institute, Boston, MA, USA 

Nitric Oxide and the Platelet:  Role in Platelet Formation

and Function

 

Nitric Oxide Insufficiency and Arterial Thrombosis

 

 

Peter J. BARNES

National Heart and Lung Institute, London, UK

 

Nitric Oxide and Airway Function in Health and in Disease

 

Exhaled Nitric Oxide in the Lung Disease

 

 

Paul VANHOUTTE

I.R.I.S, Courbevoie, France

 

Endothelial Dysfunction and Cardiovascular Disease

 

Endothelium-Derived Hyperpolarizing Factor: an Alternative to Nitric Oxide?

 

 

Bernd MAYER

Karl-Franzes Universitat, Graz, Austria

 

Biological Chemistry of Nitric Oxide/Superoxide/Peroxynitrite

 

NOS Enzymology: the Role of Tetrahydro-biopterine

 

 

Harald SCHMIDT

Rudolf-Buchheim-Institute for Pharmacology, Giessen, Germany 

 

sGC Biochemistry and Expression

 

Role of Tetrahydrobiopterine in NOS Catalysis

 

Peroxynitrite and Nitrotyrosine, a Closer Look

 

 

Tedeusz MALINSKI

Oakland University, Rochester, MI, USA 

 

Measurement of Nitric Oxide in Cardiovascular System

 

Role of Nitric Oxide in Ischemia of Brain and Heart

 

 

Richard G. KNOWLES

Glaxo Wellcame, Stevenage, UK

 

NOS Isoforms and Therapeutical Potential of Their Selective Inhibition

 

Physiological and Pathophysiological Roles of nNOS

 

Discovery and Characterisation of Highly Selective iNOS Inhibitors

 

 

Patrick VALLANCE

University College London Medical School, London, UK

 

Control of NO Pathways in Human Vasculature

 

Inflammation and Endothelial Function

 

 

Kay BRUNE

University of Erlangen-Nürnberg, Erlangen, Germany  

 

Nitric Oxide and Prostaglandins in Regulation of Renal Function

 

Role of Nitric Oxide in Pain Reception and Analgesia

 

 

Richard J. GRYGLEWSKI

Jagiellonian University, Cracow, Poland

 

Pharmacology of Endothelial Nitric Oxide, Prostacyclin and Plasminogen Activator

 

 

Chris THIEMERMANN

The William Harvey Research Institute, London, U.K

 

Nitric Oxide and Circulatory Shock

 

Nitric Oxide, Peroxynitrite, PARS and Reperfusion Injury

 

 

Massimo Di ROSA

University of Napoli, Italy

 

Nitric Oxide and Inflammation

 

 

Galen M. PIEPER

Medical College of Wisconsin, Milwaukee , WI, USA

 

Role of Nitric Oxide in Cardiac Transplant Rejection: Documentation by EPR Spectroscopy and Other Techniques

 

 

Agnes VEGH

Albert Szent-Gyorgy Medical University, Szeged, Hungary

 

Role of Nitric Oxide in Cardioprotection by Ischaemic Preconditioning

 

 

Bohuslav OŠTADAL

Academy of Sciences, Prague, Czech Republic

 

Nitric Oxide in Developing Heart

 

 

Pietro MINUZ

University of Verona, Italy

 

Nitric Oxide and Blood Coagulation

 

 

 

R. GRYGLEWSKI - P. MINUZ - L. FONTANA - G.P. VELO

DIRECTORS OF THE COURSE

 

P.BENIGNO - L. RAUSA - G.P. VELO

DIRECTORS OF THE SCHOOL

 

ZICHICHI

DIRECTOR OF THE CENTRE