SIF - Società Italiana di Farmacologia

"SIF - Risorse On-line"


Società Italiana di Farmacologia

GUIDA ALLE RISORSE FARMACOLOGICHE SULLA RETE

 

FARMACOGENETICA E FARMACOGENOMICA

 

 


ENGLISH VERSION


 

 

Lo scopo principale di questa pagina Web è quello di fornire una guida, all'interno di quel mare magnum di informazioni che è internet, a tutti coloro che già lavorano nel campo della farmacogenetica e della farmacogenomica ma anche a chi, per la prima volta, desidera avvicinarsi a questa innovativo settore della farmacologia.

Domande e commenti sono sempre bene accetti…

 

 

Home Page of the Human Cytochrome P450 (CYP) Allele Nomenclature The main function of this Web page is to encourage scientists worldwide to speak the same language and to avoid "home-made" allelic designations that can confuse the nomenclature system and the scientific literature, and it contains the recommended nomenclature for the human polymorphic CYP genes.
PharmGKB: the Pharmacogenetics knowledge Base PharmGKB curates information that establishes knowledge about the relationships among drugs, diseases and genes, including their variations and gene products. Our mission is to catalyze pharmacogenomics research.
Cytochrome P450 This Web-page is intended as an introduction to CYP and its importance in clinical medicine.
Cytochrome P450 Drug Interaction Table This table is designed as a hypothesis testing, teaching and reference tool for physicians and researchers interested in drug interactions that are the result of competition for, or effects on the human cytochrome P450 system.
Directory of P450-containing Systems The goal of this www Directory is to facilitate access to electronic resources world-wide for all researchers working in the field of P450 proteins and P450-containing systems.
Human Genome Variation Database (HGVbase) The objective of HGVbase (the Human Genome Variation Database) is to provide an accurate, high utility and ultimately fully comprehensive catalog of normal human gene and genome variation, useful as a research tool to help define the genetic component of human phenotypic variation.
dbSNP In collaboration with the National Human Genome Research Institute, The National Center for Biotechnology Information has established the dbSNP database to serve as a central repository for both single base nucleotide subsitutions and short deletion and insertion polymorphisms.
ALFRED: The Allele Frequency  Database A resource of gene frequency data on human populations supported by the U. S. National Science Foundation.
Human Genome Project (HGP) Human Genome Project Information.
Cytochrome P450 Homepage An excellent and updated Web page on CYP450.
HapMap The International HapMap Project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States to develop a public resource that will help researchers find genes associated with human disease and response to pharmaceuticals.
National Center for Biotechnology Information SNPs: Variations on a Theme.
National Center for Biotechnology Information One Size does not Fit All:
The Promise of Pharmacogenomics.
The Pharmacogenomics Portal The official portal for pharmacogenomics supported by the German University of Applied Sciences Bonn-Rhein-Sieg,PharmGenomics and the ikfe Institute for Clinical Research and Development.
Fondazione I.B.D. In questa pagine web è possibile trovare un protocollo di studio farmacogenetico in pazienti affetti da malattie infiammatorie croniche intestinali (IBD) sottoposti a terapia con tiopurine.

 

 


 

In questa sessione sono disponibili alcuni documenti in pdf che a vario titolo
trattano di farmacogenetica e farmacogenomica

 

Sperimentazione farmacogenetica: pubblicazione dei risultati degli studi clinici  
Concepts and Tools in Pharmacogenomics  
Submissions and Labels in Regulatory Pharmacogenomics  
Linee Guida per l’Istituzione e l’Accreditamento delle Biobanche 2006
Linee Guida per i protocolli clinici di Ricerca Genetica 2006
Application of Pharmacogenomics in Clinical Pharmacology 2006
Methotrexate pharmacogenomics 2006
Uridine Diphosphate Glucuronosyltransferase (UGT) 1A1 and Irinotecan: Practical Pharmacogenomics Arrives in Cancer Therapy 2006
Cancer Pharmacogenomics: Powerful Tools in Cancer Chemotherapy and Drug Development 2005
How Pharmacogenomics Will Play a Role in the Management of Asthma 2005
Intestinal barriers to oral drug absorption: Cytochrome P450 3A and ABC-transport proteins 2005
Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between β-agonist and corticosteroid pathways 2005
Personalised medicines: hopes and realities 2005
Pharmacogenetics and Human Molecular Genetics of Opiate and Cocaine Addictions and Their Treatments 2005
Pharmacogenetics of outcome in children with acute lymphoblastic leukemia 2005
Pharmacogenomics of Antihypertensive Treatment & Clinical Pharmacological Studies of Digoxin Treatment 2005
Pharmacogenomics: The Future of Healthcare 2005
Pharmacotherapy and Pharmacogenetics of Nicotine Dependence 2005
Qualitative and Quantitative Assessment of Cytochrome P450 mRNA in Humans: Studies in the Liver, Blood and Gatrointestinal Mucosa 2005
Autonomic Nervous System Pharmacogenomics: A Progress Report 2004
Irinotecan Pharmacogenetics: Is It Time to Intervene? 2004
Microarray Technology for Genotyping in Pharmacogenetics 2004
Pharmacogenetics of Psychotropic Drug Response 2004
Pharmacogenetics - Expectations and reality 2004
Principles of pharmacogenetics: implications for the anaesthetist 2004
Serotonin Transporter: Gene, Genetic Disorders, and Pharmacogenetics 2004
Cardiovascular Pharmacogenomics 2003
Characteristics of cytochrome P450-catalysed drug metabolism with focus on a black Tanzanian population 2003
Cytochrome P450 2C9, 2C19 and 2D6 genetic polymorphisms: Evaluation of genotyping as a tool for individualised treatment 2003
Pharmacogenetics: potential for individualized drug therapy through genetics 2003
Inheritance and Drug Response 2003
Pediatric Asthma: An Approach to Pharmacogenetics Analysis 2003
Pharmacogenetics of drug metabolizing enzymes with special emphasis on Ethiopians 2003
Pharmacogenomics 2003
Pharmacogenomics - Drug Disposition, Drug Targets, and Side Effects 2003
Significance of polymorphisms in human xenobiotic metabolising enzymes 2003
Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis? 2003
Pharmacogenetics in rheumatology: the prospects and limitations of an emerging field 2002
Pharmacogenetics of Asthma 2002
Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability 2002
Pharmacogenetics, ethical issues: review of the Nuffield Council on Bioethics Report 2002
Pharmacogenomics in Endocrinology 2002
Pharmacogenomics of Human UDP-Glucuronosyltransferases and Irinotecan Toxicity 2002
Cytochrome P450 isoform-specific in vitro methods to predict drug metabolism and interactions 2001
Effects of induction and inhibition of Cytochrome P-450 enzymes on the pharmacokinetics and pharmacodynamics of oral antidiabetic drugs 2001
Function, Expression and Polymorphism of Human Alcohol Dehydrogenase 3/Glutathione-Dependent Formaldehyde Dehydrogenase 2001
Invited Review: Pharmacogenetics of estrogen replacement therapy 2001
Pharmacogenetic Studies of Antihypertensive Treatment: With Special Reference to the Renin-Angiotensin-Aldosterone System 2001
Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism 2001
The role of pharmacokinetics, drug interactions and pharmacogenetics in the acquired long QT syndrome 2001
Xenobiotic-metabolizing cytochrome P450 enzymes in human lung 2001
Assessing the Cost-Effectiveness of Pharmacogenomics 2000
Cytochrome P450 1B1 (CYP1B1) Pharmacogenetics: Association of Polymorphisms with Functional Differences in Estrogen Hydroxylation Activity1 2000
Functional polymorphisms of the human multidrug resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo 2000
Pharmacogenetics 2000
Pharmacogenetics and Pharmacogenomics: Public Policy and Bioethical Issues Associated with Patents for Drug Development 2000
Pharmacogenomics: the genomics of drug response 2000
Pharmacogenomics: The Promise of Personalized Medicine 2000
Significance of polymorphisms in CYP2A6 gene 2000
Human Thiopurine Methyltransferase Pharmacogenetics 1998
Pharmacogenetics in Biological Perspective 1997
Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency 1997
β2-Adrenergic Receptor Pharmacogenetics 1997

 

 


PAGINA GESTITA DA:

Roberto Canaparo, Ph.D.

Dipartimento di Anatomia, Farmacologia e Medicina Legale. Sezione di Farmacologia Università degli Studi di Torino

Telefono studio: 0116707804

E-mail: roberto.canaparo@unito.it

Loredana Serpe, MD, Ph.D.

Dipartimento di Anatomia, Farmacologia e Medicina Legale. Sezione di Farmacologia Università degli Studi di Torino

Telefono studio: 0116707804

E-mail: loredana.serpe@unito.it

 

Maria Gabriella Scordo, MD, Ph.D.

Dipartimento di Medicina e Farmacologia Clinica e Sperimentale. Sez. di Farmacologia

Università degli Studi di Messina

Telefono studio: 0902213647

E-mail: gabriella.scordo@tiscalinet.it

 



Ultimo aggiornamento/revisione: Gennaio 2007